Advocacy is one of the many powerful tools that PATH uses to achieve its mission. By influencing the priorities and actions of decision-makers at all levels of government, in countries around the world, PATH works to create a policy environment that supports good health. The stories in this resource are from Africa and Asia. They illustrate how PATH uses a 10-part approach to advocacy to achieve lasting policy change. The approaches are not stringent guidelines, but rather a resource that can help global health implementers and advocates plan more deliberately to develop strategies to achieve policy goals. Although these examples are specific to particular countries and health issues, the methods used to accomplish policy objectives can be practiced in a variety of settings to address a myriad of issues.